tissue engineering skin and pigmentation
Specialists in skin tissue engineering, we have developed a 3D reconstructed skin pigment that can serve as model for studying normal skin or skin disease (from patient cells).
We have developed over 15 years expertise in the evaluation of UV and active ingredients including photoprotection and pigmentation, for different companies (Expansciences, Pierre Ricaud, Silab, Pierre Fabre Dermatology, LVMH …)
- Pathophysiological study from biopsies of patients (immunohistochemistry, transcriptomics …)
- Cutaneous pathology modeling using biopsies from patients or genetically modified cells
- Evaluation of molecules modulating pigmentation on monolayer co-culture or 3D model
- Evaluation of molecules modulating epidermal differentiation on reconstructed epidermis
Coordinator: Dr Muriel CARIO-ANDRE